Author: Charles Frank

Ciprofloxacin Oral Route Side Effects

Call your doctor right away if you have any serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency. Cipro belongs to a class of antibiotics called fluoroquinolones. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery. Other side effects not listed may also occur in some patients.

Cipro tablets are nearly white to slightly yellowish, film-coated, oblong-shaped tablets. Each Cipro 500 mg tablet contains 500 mg of ciprofloxacin as ciprofloxacin HCl (287.5 mg, calculated as ciprofloxacin on the dried basis) and ciprofloxacin† (212.6 mg, calculated on the dried basis). Each Cipro 1000 mg tablet contains 1000 mg of ciprofloxacin as ciprofloxacin HCl (574.9 mg, calculated as ciprofloxacin on the dried basis) and ciprofloxacin† (425.2 mg, calculated on the dried basis).

Ciprofloxacin may lower the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections.

Ciprofloxacin Tablets

Ciprofloxacin is in a class of antibiotics called fluoroquinolones. Ciprofloxacin is known to be substantially excreted by the kidney, and the risk of adverse reactions may be greater in patients with impaired renal function. No alteration of dosage is necessary for patients greater than 65 years of age with normal renal function.

Concomitant administration of tizanidine and CIPRO is contraindicated due to the potentiation of hypotensive and sedative effects of tizanidine [see CONTRAINDICATIONS]. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for CIPRO and any potential adverse effects on the breastfed child from CIPRO or from the underlying maternal condition. Advise patients to stop taking CIPRO if they experience an adverse reaction and to call their healthcare provider for advice on completing the full course of treatment with another antibacterial drug. Crystals of ciprofloxacin have been observed rarely in the urine of human subjects but more frequently in the urine of laboratory animals, which is usually alkaline [see Nonclinical Toxicology].

1. If your doctor prescribes ciprofloxacin for your child, be sure to tell the doctor if your child has or has ever had joint-related problems.
2. Other drugs may interact with ciprofloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products.
3. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

However, you may not notice improvement in your symptoms for a few days. Cipro XR extended-release tablets are only approved for treating urinary tract infections (UTIs). The typical dosage for urinary tract infections (UTIs) is 250 to 500 mg every 12 hours for 3 to 14 days.

Who should not use ciprofloxacin?

Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products with your meals, but do not use them alone when taking this medicine. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.

The Food and Drug Administration (FDA) advises to avoid using expired medications. This means it works against many different types of bacteria. However, many bacteria have grown to be resistant to Cipro.

Talk to your healthcare provider about your risks if you are in one of these age groups. Peripheral neuropathy (PN) is a condition in which damage to your nerves causes pain, burning, tingling, numbness, or weakness in your arms, hands, legs, or feet. It should not be used in people who have a history of this condition. Liver damage, also called hepatotoxicity, can happen when taking ciprofloxacin. Call your healthcare provider right away if you have any of the following symptoms of liver damage. Stop using ciprofloxacin and get medical help right away if you develop any tendon pain or swelling.

The clinical significance of this interaction has not been determined. In preliminary studies in patients with stable chronic liver cirrhosis, no significant changes in ciprofloxacin pharmacokinetics have been observed. The kinetics of ciprofloxacin in patients with acute hepatic insufficiency, have not been fully studied. In patients with reduced renal function, the half-life of ciprofloxacin is slightly prolonged. Dosage adjustments may be required [see Use In Specific Populations and DOSAGE AND ADMINISTRATION]. With oral administration, a 500 mg dose, given as 10 mL of the 5% CIPRO Suspension (containing 250 mg ciprofloxacin/5mL) is bioequivalent to the 500 mg tablet.

What should I tell my healthcare provider before using ciprofloxacin?

If your or your child’s symptoms do not improve within a few days, or if they become worse, check with your doctor. It is very important that your doctor check your or your child’s progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it. Blood and urine tests may be needed to check for unwanted effects.

Side effects in children

No, you should not crush or chew Cipro or Cipro XR extended-release tablets. Cipro is a brand-name drug that’s also available in generic form. The generic form of Cipro and cephalexin cost about the same.

A total of 335 ciprofloxacin-and 349 comparator-treated patients were enrolled. Ciprofloxacin is used to treat bacterial infections in many different parts of the body. Ciprofloxacin oral liquid and tablets are also used to treat anthrax infection after inhalational exposure. This medicine is also used to treat and prevent plague (including pneumonic and septicemic plague). Ciprofloxacin may mask or delay the symptoms of syphilis. Ciprofloxacin comes as a tablet, a suspension (liquid), and an extended-release tablet to take by mouth with or without food.

Even if you start to feel better, do not stop taking Cipro. In many cases, it’s important to finish the entire treatment to make sure the infection doesn’t come back. If you don’t have insurance, you can ask your doctor or pharmacist about online pharmacy options.

Data sources include Micromedex (updated 3 Mar 2024), Cerner Multum™ (updated 4 Mar 2024), ASHP (updated 12 Feb 2024) and others. In rare cases, ciprofloxacin may cause damage to your aorta, the main blood artery of the body. Get emergency medical help if you have severe and constant pain in your chest, stomach, or back.